REVIEWS & Publications

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  • Musiek ES, Holtzman DM. Three dimensions of the amyloid hypothesis: time, space and ‘wingmen’. Nature Neuroscience, 2015, 18(6):800-806.
  • Viola KL, Klein WL. Amyloid β oligomers in Alzheimer’s disease: pathogenesis, treatment, and diagnosis. Acta Neuropathologica, 2015, 129:183-206.
  • Goure WF, Krafft GA, Jerecic J, Hefti F. Targeting the proper amyloid-beta neuronal toxins: a path forward for Alzheimer’s disease immunotherapeutics. Alzheimer’s Research & Therapy, 2014, 6:42.
  • Lensé SE. Toxic oligomer species of amyloid-β in Alzheimer’s disease, a timing issue. Swill Medical Weekly, 2014, 144:w14021.
  • Hayde EY, Teplow DB. Amyloid β-protein oligomers and Alzheimer’s disease. Alzheimer’s Research & Therapy, 2013, 5:60.
  • Moreth J, Mavoungou C, Schindowski K. Passive anti-amyloid immunotherapy in Alzheimer’s disease: What are the most promising targets? Immunity & Aging, 2013, 10:18.
  • Walsh DM, Teplow DB. Alzheimer’s Disease and the Amyloid β-Protein. Progress in Molecular Biology and Translational Science, 2012, 106:101-124.

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  • Globular Assembly of Amyloid Beta Protein and Uses Thereof: U.S. Patent 4,666,829; Canadian Patent 2,381,323; European Patent EP1200470; Japan Patent 4,796,725.
  • Amyloid Beta Protein (Globular Assembly and Uses Thereof): U.S. Patents 6,218,506 & 7,638,283; Canadian Patent 2,279,555; European Patent EP0998495; Japanese Patent 3,512,815; Mexican Patent 245340.
  • Monoclonal Antibodies that Target Pathological Assemblies of Amyloid Beta (Abeta): U.S. Patent 8,507,206.
  • Compositions and Methods for the Enhancement of Soluble Amyloid Beta Oligomer (ADDL) Uptake and Clearance: U.S. Patent 7,964,359.
  • Anti-ADDL Antibodies and Uses Thereof: U.S. Patents 7,780,963, 7,811,563, 8,128,930, 8,383,113, 8,889,138; Australian Patents AU2005306997 & AU2012232964; Indian Patent 251624; Japanese Patents 5173426 & 5634975.
  • Anti-ADDL Monoclonal Antibody and Use Thereof: U.S. Patent 7,731,962, 8,105,593, 8,420,093; European Patent EP1940466; Japanese Patent 5289963; Patent Pending in other countries
  • Method for Detection of Amyloid Beta Oligomers in a Fluid Sample and Uses Thereof: Patent Pending
  • Antibodies, Kit and Method for Detecting Amyloid Beta Oligomers: Patent Pending.
  • Method for Treating a Disease Associated with Soluble, Oligomeric Species of Amyloid Beta 1-42: Patent Pending.